产品货号：
Z31578
中文名称：
CDK4抗体
英文名称：
Anti-CDK4 Antibody (Clone#1529CT850.162.73)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CDK4 Antibody (Clone#1529CT850.162.73) |
| 指标别名 | CDK4;Cell division protein kinase 4;CMM3;cyclin dependent kinase 4;PSK J3 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC |
| 基因名称 | CDK4 |
| 克隆号 | 1529CT850.162.73 |
| 抗体来源 | Mouse |
| 免疫原 | This CDK4 antibody is generated from a mouse immunized with a recombinant protein. |
| 计算分子量 | 34kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G (1)/S transition.Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G (1) phase.Hypophosphorylates RB1 in early G (1) phase.Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity.Component of the ternary complex,cyclin D/CDK4/CDKN1B,required for nuclear translocation and activity of the cyclin D-CDK4 complex. |
| Uniprot ID | P11802 |
相关搜索：CDK4抗体，CDK4单抗，Anti-CDK4 Antibody (Clone#1529CT850.162.73)